Phytotherapeutic approaches to PCOS: Key plant species and their therapeutic potential

Polycystic Ovary Syndrome (PCOS) is a very common multifactorial endocrine disorder that

affects women of reproductive age, characterized by hormonal imbalance, insulin resistance,

chronic anovulation together with polycystic ovaries. Although conventional pharmacological

treatments are effective, but they have side effects and do not manage all features of syndrome.

Hence, there is an emerging interest in plant-based therapies that are well recognized for their

holistic action and safety profile. Historically, medicinal plants have been used in various traditional

medicine systems to promote gynecologic health and are rich source of bioactive compounds

(Flavonoids, alkaloids and phytoestrogens) which have hormone regulatory, insulin sensitizing,

anti-inflammatory and antioxidant properties. This review determined the medicinal potential of

plants based on their phytochemical composition and their beneficial effects on PCOS symptoms

and review plant species efficacious against PCOS. Synthesizing scientifically validated research

and finding the underexplored medicinal plant species, to integrate integrate them in modern

therapeutic strategies to innovative, sustainable and multitarget treatments for PCOS.