Reproductive disorders in domestic animals necessitate innovative therapeutic approaches. This review examines the therapeutic potential of morin hydrate (3,5,7,2',4'-pentahydroxyflavone), a flavonoid present in Moraceae family, to treat reproductive disorders in males and females. Morin hydrate is potent anti-inflammatory and antioxidant, mitigates oxidative stress and inflammation, which causes reproductive abnormalities. It has antimicrobial activity and inhibits pathogenic microorganisms. Morin also alleviates reproductive conditions (testicular abnormalities, ovarian cysts, ovulation failure and endometritis) enhance crucial enzyme activities and prevent lipid peroxidation, hence, beneficial to both male and female reproductive health.