Antifungal potential of two new triterpenoidal glycosides from the Albizia kalkora against Fusarium oxysporum f. sp. lycopersici
Antifungal potential of two new triterpenoidal glycosides from the Albizia kalkora against Fusarium oxysporum f. sp. lycopersici
- Author(s) Muhammad Afzal, Ejaz Ahmed, Ahsan Sharif and Arshad Javaid
- Year: 2023
- Month: September
- Volume: 60
- Pages: 83-92
We isolated two new triterpenoidal glycosides from Albizia kalkora (Roxb.) Prain and assessed their fungicidal effects against plant pathogenic fungus Fusarium oxysporum f. sp. lycopersici (FOL) causing wilt in tomato crop. The new triterpenoidal glycosides [albizioside A (1) and albizioside B (2)] were isolated from the chloroform soluble fraction of A. kalkora extract. Their structures were elucidated by IR, 1D and 2D-NMR and mass spectrometry. In-vitro antifungal studies showed that compound 1 had promising antifungal properties causing 89.3 % growth inhibition as compared to 90.0 % inhibition by synthetic fungicide benomyl at 200 mg mL-1. Compound 2 showed 73.3 % inhibition in fungal growth at the same concentration. This study concluded that both the phytochemicals may be developed as natural fungicides to avoid the harmful effects of synthetic fungicides. Furthermore, derivatives of both the phytochemicals may also enhance their antifungal properties.
